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Rev Inst Med Trop Sao Paulo ; 57(2): 165-7, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25923897

RESUMEN

Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.


Asunto(s)
Antifúngicos/farmacología , Candida albicans/efectos de los fármacos , Candida tropicalis/efectos de los fármacos , Nanopartículas del Metal , Plata/farmacología , Humanos , Pruebas de Sensibilidad Microbiana
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